The present study examines the role of personality in the relationship between bullying at work and the subjective well-being of employees. The study was conducted with 359 participating employees of administrative bodies, the police force, and the health care sector. Four selected groups of persons with various personality profiles based on the 5-factor model underwent analysis. The obtained results attest to a protective role of a configuration of low neuroticism, high agreeableness, and high conscientiousness and a configuration of low neuroticism, high extraversion, and high openness to experience.